Sonication for high throughput systems
Pinned lid design enables sonication of 96- and 384-well microwell plate formats with disposability to prevent cross-contamination
MatriCal introduces the SonicMan high throughput sonicationsystem for 96 and 384-well microwell plate formats.
Applicationsof the SonicMan include resuspending stored compounds in HTS;resolubilising compounds in synthesis; shearing genomic data intosmall fragments for PCR amplification; extracting targetproteins, RNA/DNA, and enzymes via cell lysis and membranedisruption; mixing low volume assays; driving sonochemicalreactions; and transfecting eukaryotic cells.
"The SonicMandemonstrates how a massively parallel sonication system designedto work in 96/384/1536 formats can be used to drive compoundsback into solution," explains Kevin Oldenburg, president ofMatriCal.
This technology relies on a pinned lid that is placedon a microplate (96 or 384 well).
The pins insert through the lidand into the sample contained within the plate.
A sonic horn isbrought into contact with the lid and the sonic energy istransferred into the sample.
As scientists are highly consciousof cross contamination, the lid has been developed as adisposable part.
The pinned lid is designed to ensure sampleintegrity with no well-to-well cross contamination.
Matrical Bioscience is offering a plate adapter for use with the Sonicman automated standalone instrument for high-throughput sonication.
Matrical has introduced the Vial Weighing Station, a module that offers a single vial capture mechanism to weigh up to 210g of liquids, solids or powders.
Matrical Bioscience has introduced the Matrimix guide tube to be used exclusively with the Matrimix spinner flask.
April 07 2009 - Process Analysis and Automation (PAA) and Matrical Bioscience have partnered and will use their combined product portfolios and support teams in the life-science research market.
Matrical Bioscience is offering laser-etched 2D barcoded storage tubes in a 96- and 384-well format.