Storage technology supports drug discovery at Nottingham University
Academia steps up to the high throughput screening challenge with state-of-the-art compound storage facility.
TTP Labtech is enabling a successful new venture at the University of Nottingham’s Centre for Biomolecular Science, with its comPOUND sample storage system and comPILER high throughput, tube-to-plate processing system.
The fully automated state-of-the-art facility for the Managed Chemical Compound Collection (MCCC) provides storage for more than 100,000 diverse drug-like small molecules for high throughput compound screening.
The facility is key, not only to the University’s drug discovery research but also provides services to pharmaceutical and biotech industry partners, generating important growth potential for the University.
The comPOUND modular system provides a compact and secure, fully automated storage and dispensing facility for chemical and biological compound libraries.
Up to 100,000 1.4 mL tubes or 200,000 0.5 mL microtubes can be stored per unit in a temperature controlled, dry, inert, hermetically sealed environment; ensuring sample integrity.
Sample storage in microtube format allows cherry picking of only the samples of interest and mitigates risks of sample degradation from unnecessary freeze/thaw cycles, inherent with plate-based systems.
Prof Peter Fischer, Director, Centre for Biomolecular Sciences, University of Nottingham, commented, “Translational research is a key focus in the University, with a strong track record in pharmaceutical sciences. Worldwide pharmaceutical companies are turning to academic partners to support compound screening for drug R&D.
“The long-term vision is to provide a unique compound collection attractive to academic and pharma partners – especially SMEs without their own collections”.