DSC software analyses changes in protein stability
GE Healthcare
Microcal VP-Capillary software
GE Healthcare has launched the Microcal VP-Capillary differential scanning calorimetry (DSC) software, which provides the automated, high-throughput analysis of changes in protein stability.
This analytical system enables the early characterisation of the stability of molecules in solution, providing critical information in protein engineering, from pre-formulation and process development to the formulation of the final biopharmaceutical product.
The new software minimises the data analysis bottleneck and simplifies experiment design and setup, according to the company.
By providing a single graphical user interface for selecting and entering all sample and experiment run parameters, assay development time is said to be kept to a minimum.
The software also streamlines the workflow, enabling flexible instrument scheduling, while the automated data sorting and analysis capabilities can reduce the time required for the analysis of a typical experiment from days to hours.
The Microcal VP-Capillary DSC system works by allowing protein unfolding to be studied quickly without the use of labels or artificial probes as it determines the heat absorbed by the sample as the protein unfolds, giving a measure of thermal stability and an indication of long-term stability.
The system is designed to allow the study of up to 50 samples per day with fully automated cell filling, injection and cleaning functions, thereby enabling unattended operation.
The software is available with all new Microcal VP-Capillary DSC systems and as an upgrade for current users.
Related images
More stories
GE Healthcare unveils Capto Core 700
GE Healthcare Life Sciences has launched Capto Core 700 chromatography medium for viruses and other large biomolecules.
Hyperfilm Blue, detects chemiluminescent signals
GE Healthcare is now stocking Amersham Hyperfilm Blue, a blue sensitive film that enables rapid, qualitative results for the detection of chemiluminescent signals in different blotting assays.
GE offers gel system for protein electrophoresis
GE Healthcare's horizontal Amersham ECL Gel System is designed for high-quality protein electrophoresis enabling efficient, high-quality and reproducible protein separation.
Cards enable colourless biosample fluid collection
GE Healthcare's new Whatman Indicating FTA DMPK Cards enable the collection of colourless biosample fluids, such as plasma, urine and CSF, for use in pharmacokinetic and toxicokinetic studies.
Software ensures cell analyser system is compliant
GE Healthcare has introduced the IN Cell Analyzer Compliance Manager, which is designed to aid GxP compliance of the IN Cell Analyzer 2000 system.
