Prototype lyophilised syringe system developed
Arte Corporationcontact supplier
Companies collaborate on a new type of dual chamber prefillable syringe for freeze-dried pharmaceuticals.
Arte Corporation and ProJect Pharmaceutive have joined forces to provide a innovative dual chamber syringes for the global pharmaceutical market.
The device, called Lyo-DCPS, will be delivered in standard nests and tubs to comply with the industrial standard for aseptic filling of nested syringes.
The abbreviation Lyo-DCPS stands for lyophilised dual chamber prefillable syringe.
Like conventional mono chamber syringes Lyo-DCPS will be delivered in standardised nests and tubs and can be filled on widely used nested syringe fillers.
The diluent is filled first and can be autoclaved as required by international guidelines. The drug solution is filled into the second chamber and completely sealed on the filling line before entering the freeze drier.
Due to its special design, the system opens by itself within the freeze drier enabling lyophilisation of the drug solution in presence of the diluent.
The development has reached pilot stage and lyophilisation of first customers´ products in the new device has been performed successfully.
Sterile nested Lyo-DCPS for GMP manufacturing of drug products will be available early 2013.